Determine of appropriate concentration of propofol anesthetic drug in Benni (Barbus sharpeyi)

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Abstract

The propofol anesthetic drug was used on 60 farmed Benny fish (Barbus sharpeyi) with
mean (±SD) weight and length 99±30g and 208±19.2cm, respectively. The fish were divided
into 6 treatments of 10 fish. The treatment 1(control group) was not exposed to any type of
anesthesia material. Five treatments were exposed to propofol anesthetic drug with 2, 4, 6, 8
and 10mg/l concentration by immersion method. The mean time of initial anesthesia, mean
time of total anesthesia, mean recovery time from anesthesia and survival rate were
investigated in treatments. Results showed that increasing of propofol dose had reduced with
time of initial anesthesia. Treatment 2 and 3 with 2 and 4mg/l of propofol were significantly
different with treatment 5 and 6 with 8 and 10mg/l of propofol material. The mean time of
total anesthesia in treatments 5 and 6 with 8 and 10mg/l of propofol material were
significantly different with treatments 2, 3 and 4 with 2, 4 and 6mg/l of propofol material,
respectively. The mean (±SD) recovery time from anesthesia in Benny fish in treatment
5(8mg/l) was highest amount (428±33S) compared to other treatments. Survival rate in all
treatment except treatment 6 (70%) was 100%. Overall, it appears that propofol material was
as an anesthetic drug that present experiment showed safety. In 4-6mg/l concentration had the
best performance in total anesthesia and recovery to initial condition.

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Iranian Scientific Fisheries Journal
Volume 21, Issue 2 - Serial Number 79
March and April 2013
Pages 133-142

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