نویسندگان
چکیده
کلیدواژهها
عنوان مقاله [English]
نویسندگان [English]
The effects of dietary selenium (Se) were investigated on the oxidative stress of beluga,
Huso huso, fed high dietary copper (Cu). The basal diet with high Cu (50mg Cu/kg) was
supplemented with low (0mg Se/kg, HCuLSe), adequate (11mg Se/kg, HCuNSe) and 5Ã
adequate (55mg Se/kg, HCuHSe) of Seandfed to fish with initial body mean (±SD) weight
14.96 ± 1.39g for 12 weeks. Basal diets containing adequate Se (11mg Se/kg) and adequate
Cu (10mg Cu/kg) were used as controls (NCuNSe). Weight gain, specific growth rate and
condition factor for fish fed the HCuHSe diet was significantly lower than fish that fed the
other diets. Se and Cu content was positively correlated with dietary Se and Cu
concentrations. Hepatic Se concentration was higher in fish fed the HCuHSe diet than fish
that fed other diets. Thiobarbituric acid-reactive substances (TBARS) were significantly
lower. Whereas, Glutathione peroxidase activity activities were significantly higher in liver
tissue of fish fed HCuHSediet than those fish fed other diets. Plasma total immunoglobulin
concentration and lysozyme activity were higherin fish fed the NCuNSe diet, followed by fish
fed the HCuNSe diet, and were lower in fish fed the HCuHSe diet. The results indicated that
optimum levels of Cu and Se ingestion induced an oxidative stress in beluga and improved
their immune response. High dietary Se (5Ãadequate) supplementation reduced the oxidative
stress and depressed the immune response of the fish.
*Corresponding author
کلیدواژهها [English]
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